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Related Research FOXO4-DRI: Senolytic Peptide Mechanism and the p53-FOXO4 Axis FOXO4-DRI is a D-retro-inverso peptide that selectively kills senescent cells by disrupting the protective FOXO4-p53 interaction

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Another key regulator of lipid peroxidation and ferroptosis is nuclear factor erythroid 2-related factor 2 (Nrf2), which controls genes involved in iron metabolism and oxidative stress, such as heme oxygenase-1 (HO-1) and quinone oxidoreductase 1 (NQO1)